Rutgers-led study identifies 36 genes linked to OCD and tic disorders

A Rutgers‑led international research team has pinpointed 36 genes that significantly increase the risk of obsessive‑compulsive disorder (OCD) and chronic tic disorders. The discovery, announced by the investigators, represents the most comprehensive genetic map yet of the biological factors that contribute to these neuropsychiatric conditions.

The study combined genome‑wide association data from thousands of participants across multiple countries, enabling researchers to identify genetic variants that are strongly linked to both OCD and tic disorders. By mapping these variants to biological pathways, the team has clarified how specific genes may influence brain circuits involved in compulsive behaviors and motor tics. The findings also highlight potential targets for future therapeutic interventions and provide a framework for developing more personalized treatment strategies.

With this deeper genetic insight, scientists now have a clearer understanding of the underlying mechanisms that drive OCD and chronic tic disorders. The research paves the way for improved diagnostic tools and the eventual development of targeted therapies that address the root causes of these conditions.