New Research Uncovers Early Immune Clues for TB Development

A quarter of the global population is estimated to have been infected with Mycobacterium tuberculosis, yet only 5%–10% of those infected go on to develop active tuberculosis (TB). "The big question has always been what distinguishes people who control the infection from those who don't," says Anne O'Garra, whose lab at the Crick studies how the immune system responds to infection.