Bone marrow transplant restores peripheral immune cells in mice

The immune system, composed of specialized cells and proteins, serves as the body’s primary defense against pathogens and malignant cells. Under normal conditions it identifies and neutralizes foreign invaders with high efficiency, maintaining health across a wide range of physiological challenges.

When the system fails to respond adequately or becomes excessively active, it can contribute to disease. Insufficient immune activity may allow infections or cancer to progress, while overactive responses can lead to autoimmune disorders and chronic inflammation. Researchers continue to investigate the mechanisms underlying these imbalances to improve diagnostic and therapeutic strategies.